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George Q Daley Selected Research

Pharmaceutical Preparations

1/2020Pancreatic circulating tumor cell profiling identifies LIN28B as a metastasis driver and drug target.
1/2017Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors.
12/2016TGF-β inhibitors stimulate red blood cell production by enhancing self-renewal of BFU-E erythroid progenitors.
1/2004Mechanisms and implications of imatinib resistance mutations in BCR-ABL.
3/2003Mechanisms of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL.

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George Q Daley Research Topics

Disease

24Neoplasms (Cancer)
09/2021 - 03/2003
15BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2016 - 01/2002
13Carcinogenesis
01/2022 - 06/2004
9Leukemia
01/2019 - 04/2003
3Infections
11/2012 - 01/2002
3Teratoma (Teratoid Tumor)
08/2011 - 05/2009
2Diamond-Blackfan Anemia (Anemia, Diamond Blackfan)
10/2020 - 01/2017
2Anemia
10/2020 - 12/2016
2Neuroblastoma
01/2020 - 01/2016
2Neoplasm Metastasis (Metastasis)
01/2020 - 06/2004
2Hematologic Diseases (Blood Diseases)
01/2017 - 01/2004
2Insulin Resistance
09/2011 - 07/2010
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
08/2010 - 04/2003
1Hypoxia (Hypoxemia)
01/2022
1Lung Neoplasms (Lung Cancer)
09/2021
1Circulating Neoplastic Cells
01/2020
1Renal Hypertension
11/2019
1Cardiovascular Diseases (Cardiovascular Disease)
11/2019
1Starvation
12/2017
1Leber Congenital Amaurosis
01/2017
1Carcinoma (Carcinomatosis)
09/2015
1Liver Diseases (Liver Disease)
08/2014
1Heart Diseases (Heart Disease)
08/2014
1Nervous System Diseases (Neurological Disorders)
08/2014
1Retinal Diseases
08/2014
1Bone Marrow Failure Disorders
07/2013
1Mitochondrial Diseases (Mitochondrial Disease)
07/2013
1VLCAD deficiency
07/2013
1Stroke (Strokes)
01/2013
1Vascular Diseases (Vascular Disease)
12/2012
1Encephalitis (Encephalitis, Rasmussen)
11/2012
1Ataxia Telangiectasia (Louis Bar Syndrome)
09/2012
1Ectodermal Dysplasia (Aplasia Cutis Congenita)
05/2012
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
04/2012
1Frontotemporal Dementia (Semantic Dementia)
04/2012
1Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar)
04/2012
1Type 2 Diabetes Mellitus (MODY)
09/2011
1Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked)
09/2011
1Mucopolysaccharidosis I (Hurler Syndrome)
01/2011
1Fanconi Anemia (Fanconi's Anemia)
01/2011
1Oncogene Addiction
12/2010
1Myeloid Leukemia (Leukemia, Myelocytic)
08/2010

Drug/Important Bio-Agent (IBA)

11MicroRNAs (MicroRNA)IBA
01/2020 - 04/2008
7RNA-Binding Proteins (RNA-Binding Protein)IBA
01/2022 - 07/2009
7Oncogene Proteins (Oncogene Protein)IBA
12/2010 - 01/2002
7Imatinib Mesylate (Gleevec)FDA Link
09/2007 - 03/2003
6Proteins (Proteins, Gene)FDA Link
01/2020 - 07/2007
5Pharmaceutical PreparationsIBA
01/2020 - 03/2003
4Transcription Factors (Transcription Factor)IBA
01/2020 - 12/2005
4Phosphotransferases (Kinase)IBA
12/2016 - 03/2003
4Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
12/2010 - 01/2002
3Tyrosine Kinase InhibitorsIBA
09/2021 - 09/2007
3Messenger RNA (mRNA)IBA
09/2021 - 12/2005
3ChromatinIBA
01/2020 - 12/2009
3DNA (Deoxyribonucleic Acid)IBA
01/2020 - 04/2012
3Small Interfering RNA (siRNA)IBA
09/2015 - 05/2009
3CytokinesIBA
01/2012 - 02/2004
2Complement System Proteins (Complement)IBA
11/2019 - 02/2004
2Glucose (Dextrose)FDA LinkGeneric
09/2011 - 07/2010
2TransferasesIBA
09/2007 - 04/2003
2bcr-abl Fusion ProteinsIBA
02/2005 - 03/2003
1ErbB Receptors (EGF Receptor)IBA
09/2021
1Calmodulin (Calcium-Dependent Activator Protein)IBA
10/2020
1Protein Subunits (Protein Subunit)IBA
10/2020
1Ribosomal Proteins (Ribosomal Protein)IBA
10/2020
1Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA
01/2020
1Adrenergic Agents (Adrenergic Drugs)IBA
01/2020
1N,N,N',N'- tetrakis(2- pyridylmethyl)ethylenediamineIBA
01/2018
1ZincIBA
01/2018
1Valine (L-Valine)FDA Link
12/2017
1CateninsIBA
05/2015
1Mitochondrial DNA (mtDNA)IBA
07/2013
1T-Cell Acute Lymphocytic Leukemia Protein 1IBA
01/2013
1cadherin 5IBA
01/2013
1Toll-Like Receptor 3IBA
11/2012
1Histones (Histone)IBA
10/2012
1Lysine (L-Lysine)FDA Link
10/2012
1HeterochromatinIBA
10/2012
1Transcription Factor 3IBA
09/2012
1NF-kappa B (NF-kB)IBA
05/2012
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2012
1Sirolimus (Rapamycin)FDA Link
09/2011
1Lovastatin (Mevacor)FDA LinkGeneric
09/2011
14-phenylbutyric acid (Buphenyl)FDA Link
09/2011
1Fatty Acids (Saturated Fatty Acids)IBA
09/2011
1Retinaldehyde (Retinal)IBA
04/2011
1Iduronidase (alpha-L-Iduronidase)IBA
01/2011
1GlycosaminoglycansIBA
01/2011
1AP 24163IBA
08/2009
1Calcineurin InhibitorsIBA
06/2009
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2009
1CalcineurinIBA
06/2009

Therapy/Procedure

13Therapeutics
09/2021 - 05/2003
4Transplantation
01/2019 - 04/2002
2Drug Therapy (Chemotherapy)
12/2010 - 04/2003
1Heterologous Transplantation (Xenotransplantation)
01/2022
1Cell- and Tissue-Based Therapy (Cell Therapy)
01/2013
1Aftercare (After-Treatment)
09/2011
1Cell Transplantation
01/2011
1Oral Administration
08/2009